Table 4 |
||||||
|
Putative apoptotic mediators absent in S. cerevisiae |
||||||
|
Protein/Domain |
ASP |
SOR |
Scer |
Spom |
BAS |
Biological function/process |
|
|
||||||
|
TRAF-3 |
1 |
1 |
0 |
0 |
1 |
Caspase dependent apoptosis |
|
Mst3/STK24 |
1 |
0–1 |
0 |
2 |
0–1 |
Caspase dependent apoptosis |
|
PARP |
1 |
1 |
0 |
0 |
0 |
Caspase independent apoptosis |
|
AMID |
1–2 |
0–1 |
0 |
0 |
1 |
Caspase independent apoptosis |
|
GRIM-19 |
1 |
1 |
0 |
0 |
1–2 |
Electron transport, NADH ubiquinone oxidoreductase |
|
NDUFS1 |
1 |
1 |
0 |
0 |
1 |
Electron transport, NADH ubiquinone oxidoreductase |
|
APAF |
3–8 |
0–2 |
0 |
0 |
0 |
NTP binding, hetero-oligomerization |
|
12R-LO |
1 |
0–1 |
0 |
0 |
0 |
Peroxidation of arachidonic acid |
|
15-LO |
1 |
0–1 |
0 |
0 |
0 |
Peroxidation of arachidonic acid |
|
PTDSR/PSR |
1 |
1 |
0 |
0 |
1 |
Recognition of apoptotic cells |
|
|
||||||
|
ASP, A. fumigatus, N. fischeri, A. oryzae, A. nidulans; SOR, N. crassa, G. zeae, and M. grisea; BAS: C. neoformans and U. maydis; Scer, S. cerevisiae; Spom, S. pombe. |
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|
Fedorova et al. BMC Genomics 2005 6:177 doi:10.1186/1471-2164-6-177 |
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