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Brain microarray data for mouse chromosome 7B2-C genesa in TgPWS vs. WT mice. |
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| GenBank |
Affy ID |
Gene |
mRNA levelb |
Chr. 7 location (Mb and/or cM) |
|
| TgPWS |
WT |
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|
|
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| I. Genes centromeric of the TgPWS/TgAS deletion |
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| NM_008087 |
94337_at |
Gas2 |
4.3 (3/5) |
5.0 (2/5) |
39.3 Mb; 26.8 cM |
| 94338_g_at |
Gas2 |
43.1 (5/5) |
42.92 (5/5) |
as above |
|
| AK049836 |
97539_at |
Hrmt1l3 |
50.2 (5/5) |
44.5 (4/5) |
37.25 Mb |
| NM_016865 |
103671_at |
Htatip2 |
23.8 (0/5) |
21.0 (0/5) |
37.2 Mb |
| AY957576 |
103202_f_at |
E2F8 |
35.3 (4/5) |
30.4 (4/5) |
36.3 Mb |
| 103204_r_at |
E2F8 |
27.4 (1/5) |
21.6 (2/5) |
as above |
|
| NM_013808 |
103084_at |
Csrp3 |
4.6 (0/5) |
3.2 (0/5) |
36.3 Mb |
| NM_013643 |
100406_at |
Ptpn5 |
399.8 (5/5) |
406.1 (5/5) |
34.5 Mb |
| NM_016855 |
95304_at |
Attp |
8.5 (0/5) |
8.7 (0/5) |
34.3 Mb |
| NM_021884 |
94809_at |
Tsg101 |
56.5 (5/5) |
56.6 (5/5) |
34.3 Mb |
| NM_013580 |
93103_at |
Ldh3 |
1.7 (0/5) |
1.3 (0/5) |
34.3 Mb; 23.5 cM |
| II. Genes telomeric of the TgPWS/TgAS deletion |
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| NM_007390 |
101131_at |
Chrna7 |
86.8 (0/5) |
87.1 (0/5) |
50.1 Mb; 30.0 cM |
| NM_021366 |
160617_at |
Klf13 |
145.2 (5/5) |
155.6 (5/5) |
50.9 Mb |
| NM_018752 |
102251_at |
Trpm1 |
77.7 (1/5) |
56.7 (0/5) |
51.2 Mb; 27.0 cM |
| BC055074 |
93235_at |
BB128963 |
51.3 (5/5) |
46.0 (5/5) |
51.3 Mb |
| NM_026483 |
104022_at |
Mphosph10 |
35.9 (0/5) |
34.0 (0/5) |
51.4 Mb |
| NM_028626 |
102022_at |
Mcee |
79.6 (5/5) |
81.1 (5/5) |
51.4 Mb |
| NM_007461 |
92727_at |
Apba2 |
433.9 (5/5) |
455.8 (5/5) |
51.5 Mb; 25.5 cM |
| NM_009386 |
99935_at |
Tjp1 |
185.3 (5/5) |
142.5 (5/5) |
52.3 Mb; 28.5 cM |
| D50060 |
101196_at |
Pace4 |
78.3 (0/5) |
71.2 (0/5) |
52.9 Mb; 28.5 cM |
| NM_021336 |
101506_at |
Snrpa1 |
131.2 (5/5) |
126 (5/5) |
53.1 Mb |
| NM_024439 |
94245_at |
H47 |
141.8 (5/5) |
144.2 (5/5) |
53.1 Mb; 28.5 cM |
| NM_053080 |
98372_at |
Aldh1a3 |
13.3 (0/5) |
9.8 (0/5) |
53.4 Mb |
| NM_194070 |
93852_at |
Mef2a |
399.9 (5/5) |
417.4 (5/5) |
54.3 Mb; 33.0 cM |
| AF056187 |
102224_at |
Igf1r |
381.6 (5/5) |
339.6 (5/5) |
55.0 Mb; 33.0 cM |
|
a The primary microarray data from this experiment were reported in reference 15. As summarized in Fig. 1A, reference 15 included the data for the imprinted genes within the TgPWS/TgAS deletion that are on the MG-U74Av2 chip (Snrpn, Ndn, Magel2, Mkrn3 and Ube3a) and for non-imprinted genes within the deletion (Cyfip1, Herc2, and Gabrb3, although the latter transcript was not detectable; the p gene is also represented on the chip although not detectable in TgPWS or WT mice, and not previously reported). Additionally, a cluster of chromosome 18B3 genes were found to be abnormally expressed in TgPWS mice [15]. b mRNA levels are presented as the medians of Signal (relative abundance of a transcript), for TgPWS (n = 5) and WT (n = 5), with the number of calls as "detected" out of 5 comparison experiments in parentheses. | |||||
Stefan et al. BMC Genomics 2005 6:157 doi:10.1186/1471-2164-6-157 |
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