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List of 30 P. aeruginosa genes most strongly induced and repressed in response to hydrogen peroxide |
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| Gene (Name) |
Fold change |
p-value |
Protein (Function) |
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| Induced Genes |
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| PA5530 |
24.7 |
0.008 |
Probable MFS dicarboxylate transporter (Membrane proteins; Transport of small molecules) |
| PA1466 |
13.9 |
0.008 |
Hypothetical protein (Hypothetical, unclassified, unknown) |
| PA2288 |
10.3 |
0.008 |
Hypothetical protein (Hypothetical, unclassified, unknown) |
| PA3414 |
9.8 |
0.008 |
Hypothetical protein (Hypothetical, unclassified, unknown) |
| PA4763 (recN) |
8.3 |
0.008 |
DNA repair protein (DNA replication, recombination, modification and repair) |
| PA0182 |
6.8 |
0.024 |
Probable short-chain dehydrogenase (Putative enzymes) |
| PA3008 |
5.7 |
0.008 |
Hypothetical protein (Hypothetical, unclassified, unknown) |
| PA0670 |
5.4 |
0.008 |
Hypothetical protein (Hypothetical, unclassified, unknown) |
| PA0612 |
5.3 |
0.008 |
Hypothetical protein (Hypothetical, unclassified, unknown) |
| PA0641 |
5.0 |
0.008 |
Probable bacteriophage protein (Related to phage, transposon, or plasmid) |
| PA0671 |
5.0 |
0.008 |
Hypothetical protein (Hypothetical, unclassified, unknown) |
| PA4613 (katB) |
4.5 |
0.024 |
Catalase (Adaptation, protection) |
| PA3413 |
4.4 |
0.008 |
Hypothetical protein (Hypothetical, unclassified, unknown) |
| PA0620 |
4.2 |
0.008 |
Probable bacteriophage protein (Related to phage, transposon, or plasmid) |
| PA0615 |
4.2 |
0.008 |
Hypothetical protein (Hypothetical, unclassified, unknown) |
| PA5471 |
4.1 |
0.024 |
Hypothetical protein (Hypothetical, unclassified, unknown) |
| PA5470 |
4.1 |
0.024 |
Probable peptide chain release factor (Translation, post-translational modification, degradation) |
| PA3007 (lexA) |
4.0 |
0.008 |
Repressor protein (Adaptation, protection; Translation, post-translational modification, degradation) |
| PA0922 |
3.7 |
0.008 |
Hypothetical protein (Hypothetical, unclassified, unknown) |
| PA0635 |
3.6 |
0.008 |
Hypothetical protein (Related to phage, transposon, or plasmid) |
| PA0616 |
3.5 |
0.008 |
Hypothetical protein (Hypothetical, unclassified, unknown) |
| PA0634 |
3.5 |
0.008 |
Hypothetical protein (Related to phage, transposon, or plasmid) |
| PA0625 |
3.4 |
0.008 |
Hypothetical protein (Related to phage, transposon, or plasmid) |
| PA0636 |
3.4 |
0.008 |
Hypothetical protein (Related to phage, transposon, or plasmid) |
| PA0617 |
3.4 |
0.008 |
Probable bacteriophage protein (Hypothetical, unclassified, unknown) |
| PA0633 |
3.3 |
0.008 |
Hypothetical protein (Related to phage, transposon, or plasmid) |
| PA0637 |
3.3 |
0.008 |
Conserved hypothetical protein (Related to phage, transposon, or plasmid) |
| PA3923 |
3.3 |
0.008 |
Hypothetical protein (Hypothetical, unclassified, unknown) |
| PA4582 |
3.2 |
0.008 |
Conserved hypothetical protein (Hypothetical, unclassified, unknown) |
| PA0638 |
3.2 |
0.008 |
Probable bacteriophage protein (Hypothetical, unclassified, unknown) |
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| Repressed Genes |
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| PA2398 (fpvA) |
5.7 |
0.008 |
Ferripyoverdine receptor (Transport of small molecules) |
| PA4156 |
5.1 |
0.008 |
Probable TonB-dependent receptor (Transport of small molecules) |
| PA4230 (pchB) |
4.3 |
0.008 |
Salicylate biosynthesis protein (Transport of small molecules; Secreted Factors) |
| PA2405 |
3.9 |
0.008 |
Hypothetical protein (Hypothetical, unclassified, unknown) |
| PA2409 |
3.7 |
0.008 |
Probable permease of ABC transporter (Membrane proteins; Transport of small molecules) |
| PA5235 (glpT) |
3.4 |
0.008 |
Glycerol-3-phosphate transporter (Membrane proteins; Transport of small molecules) |
| PA4225 (pchF) |
3.3 |
0.008 |
Pyochelin synthetase (Transport of small molecules; Secreted Factors) |
| PA2407 |
3.3 |
0.008 |
Probable adhesion protein (Motility & Attachment) |
| PA2403 |
3.2 |
0.008 |
Hypothetical protein (Hypothetical, unclassified, unknown; Membrane proteins) |
| PA5479 (gltP) |
3.2 |
0.008 |
Proton-glutamate symporter (Membrane proteins; Transport of small molecules) |
| PA3009 |
3.1 |
0.008 |
Hypothetical protein (Hypothetical, unclassified, unknown) |
| PA2426 (pvdS) |
3.0 |
0.024 |
Sigma factor (Transcriptional regulators) |
| PA2404 |
3.0 |
0.008 |
Hypothetical protein (Hypothetical, unclassified, unknown; Membrane proteins) |
| PA2667 |
3.0 |
0.008 |
Conserved hypothetical protein (Transcriptional regulators) |
| PA3610 (potD) |
3.0 |
0.008 |
Polyamine transport protein (Transport of small molecules) |
| PA4555 (pilY2) |
3.0 |
0.008 |
Type 4 fimbrial biogenesis protein (Motility & Attachment) |
| PA1414 |
2.9 |
0.024 |
Hypothetical protein (Hypothetical, unclassified, unknown) |
| PA0280 (cysA) |
2.9 |
0.024 |
Sulfate transport protein (Transport of small molecules) |
| PA2408 |
2.9 |
0.008 |
Probable ATP-binding component of ABC transporter (Transport of small molecules) |
| PA4839 (speA) |
2.9 |
0.008 |
Biosynthetic arginine decarboxylase (Amino acid biosynthesis and metabolism) |
| PA4231 (pchA) |
2.9 |
0.008 |
Salicylate biosynthesis isochorismate synthase (Secreted Factors; Transport of small molecules) |
| PA0281 (cysW) |
2.8 |
0.008 |
Sulfate transport protein (Membrane proteins; Transport of small molecules) |
| PA1228 |
2.8 |
0.008 |
Hypothetical protein (Hypothetical, unclassified, unknown) |
| PA5049 (rpmE) |
2.8 |
0.008 |
50S ribosomal protein (Translation, post-translational modification, degradation) |
| PA2619 (infA) |
2.7 |
0.008 |
Initiation factor (Translation, post-translational modification, degradation) |
| PA4221 (fptA) |
2.7 |
0.008 |
Fe(III)-pyochelin receptor precursor (Transport of small molecules) |
| PA0976 |
2.7 |
0.008 |
Conserved hypothetical protein (Hypothetical, unclassified, unknown) |
| PA5446 |
2.7 |
0.048 |
Hypothetical protein (Hypothetical, unclassified, unknown) |
| PA4229 (pchC) |
2.6 |
0.008 |
Pyochelin biosynthetic protein (Transport of small molecules; Secreted Factors) |
| PA4218 |
2.6 |
0.008 |
Probable transporter (Membrane proteins; Transport of small molecules) |
Chang et al. BMC Genomics 2005 6:115 doi:10.1186/1471-2164-6-115 |
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