Table 1

Over-representation of protein domains in genes flanking UCRs. Bonferroni-corrected and uncorrected Fisher Exact Test p-values are shown for the 16 most over-represented InterPro domains. Typical transcription factor domains (DNA binding domains) are indicated in bold. A full list of all InterPro domains with P-values is given in [Additional file 3].

Domain description

INTERPRO ID

Fisher test P value

Corrected P value


HTH_lambrepressr

IPR000047

6.40E-20

5.36E-17

Homeobox

IPR001356

1.60E-12

1.34E-09

Antennapedia

IPR001827

1.37E-10

1.15E-07

Paired_box

IPR001523

2.39E-05

2.00E-02

HLH_basic

IPR001092

2.40E-05

2.01E-02

POU_domain

IPR000327

3.06E-05

2.56E-02

Homeo_OAR

IPR003654

3.08E-05

2.58E-02

TF_Fork_head

IPR001766

6.15E-05

5.15E-02

Znf_C4steroid

IPR001628

7.45E-05

6.23E-02

Hormone_rec_lig

IPR000536

1.06E-04

8.86E-02

HMG_12_box

IPR000910

1.81E-04

1.51E-01

Stdhrmn_receptor

IPR001723

2.63E-04

2.20E-01

COUP_TF

IPR003068

7.62E-04

6.38E-01

LIM

IPR001781

1.10E-03

9.18E-01

RtnoidX_receptor

IPR000003

1.28E-03

1.07E+00

FN_III

IPR003961

2.57E-03

2.15E+00


Sandelin et al. BMC Genomics 2004 5:99   doi:10.1186/1471-2164-5-99

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