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Over-representation of protein domains in genes flanking UCRs. Bonferroni-corrected and uncorrected Fisher Exact Test p-values are shown for the 16 most over-represented InterPro domains. Typical transcription factor domains (DNA binding domains) are indicated in bold. A full list of all InterPro domains with P-values is given in [Additional file 3]. |
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| Domain description |
INTERPRO ID |
Fisher test P value |
Corrected P value |
|
|
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| HTH_lambrepressr |
IPR000047 |
6.40E-20 |
5.36E-17 |
| Homeobox |
IPR001356 |
1.60E-12 |
1.34E-09 |
| Antennapedia |
IPR001827 |
1.37E-10 |
1.15E-07 |
| Paired_box |
IPR001523 |
2.39E-05 |
2.00E-02 |
| HLH_basic |
IPR001092 |
2.40E-05 |
2.01E-02 |
| POU_domain |
IPR000327 |
3.06E-05 |
2.56E-02 |
| Homeo_OAR |
IPR003654 |
3.08E-05 |
2.58E-02 |
| TF_Fork_head |
IPR001766 |
6.15E-05 |
5.15E-02 |
| Znf_C4steroid |
IPR001628 |
7.45E-05 |
6.23E-02 |
| Hormone_rec_lig |
IPR000536 |
1.06E-04 |
8.86E-02 |
| HMG_12_box |
IPR000910 |
1.81E-04 |
1.51E-01 |
| Stdhrmn_receptor |
IPR001723 |
2.63E-04 |
2.20E-01 |
| COUP_TF |
IPR003068 |
7.62E-04 |
6.38E-01 |
| LIM |
IPR001781 |
1.10E-03 |
9.18E-01 |
| RtnoidX_receptor |
IPR000003 |
1.28E-03 |
1.07E+00 |
| FN_III |
IPR003961 |
2.57E-03 |
2.15E+00 |
Sandelin et al. BMC Genomics 2004 5:99 doi:10.1186/1471-2164-5-99 |
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