Sources of variation in the mixed ANOVA model. Distribution of Mean Squares Errors by variation source are plotted for those genes with at least one tissue showing expression at a level above LN(100) (7853 genes). Note that individual women emerge as the dominant source of variation. Variation contributed by tissue storage is of approximately the same magnitude as that seen between duplicate samples within the same storage group. Boxes encompass inner quartiles, horizontal line represents the median or the second quartile, and whiskers delimit 1.5 times the interquartile range. Because of the very large number of data points, outliers were suppressed in this summary plot.
Mutter et al. BMC Genomics 2004 5:88 doi:10.1186/1471-2164-5-88