Sample size for detecting differentially expressed genes in microarray experiments

doi:10.1186/1471-2164-5-87

BMC Genomics

Volume 5

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Research article

Sample size for detecting differentially expressed genes in microarray experiments

Caimiao Wei¹ , Jiangning Li² and Roger E Bumgarner¹

¹Department of Microbiology, University of Washington, Seattle, WA 98195, USA

²Department of Pathology, University of Washington, Seattle, WA 98195, USA

author email corresponding author email

BMC Genomics 2004, 5:87doi:10.1186/1471-2164-5-87


Published:	8 November 2004

Additional files

Additional File 1:

Sample size required to detect a 1.5-, 2-, and 4-fold changes of expression level for the 90%, 75%, 50%, and 25% least variable genes for a given settings of false positive rates (α) and power (1-β). This additional file shows the estimated sample size to a 1.5-, 2, and 4-fold changes of expression level for the 90%, 75%, 50%, and 25% least variable genes for a given settings of false positive rates (α) and power (1-β) for all of the data sets referred in Table 1.

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