Figure 3.

Two methods of pooling standard deviations of M: sorting by I_avg or by I_min. The standard deviation (σ_M) is pooled by taking the moving average of the variance (σ_M²). (a) Measured (σ_M, gray) and pooled (σ_M'(I_avg), black) standard deviation of the logged ratio M, plotted against I_avg. For spots with σ_M' > σ_M, the average residual error is 0.28; for spots with σ_M' < σ_M, the average residual error is 0.31. (b) Measured (σ_M, gray) and pooled (σ_M'(I_min), black) standard deviation of M, plotted against I_min. For spots with σ_M' > σ_M, the average residual error is 0.28; for spots with σ_X' < σ_X, the average residual error is 0.31. (c) Pooled standard deviation of M (σ_M') plotted against the intensity metric used for pooling, I_avg or I_min. Data are from Dataset 3.