Table 2

Breakdown of the number of mutations in SAAPdb and their mapping to structure.

Number of Mutations

PDs

SNPs


Mapped to UniProtKB/SwissProt

13,059

48,452

Mapped to PDB

6,527

17,915

Mapped to multiple PDBs

202,566

33,369

Mapped to multiple Chains

405,497

45,699


In some cases, several hundred structures are available (e.g. haemoglobin, carbonic anhydrase, prthrombin, transthyretin, insulin, CDK2, lysozyme) and, on average there are approximately two copies of each chain in each PDB file.

Al-Numair and Martin BMC Genomics 2013 14(Suppl 3):S4   doi:10.1186/1471-2164-14-S3-S4

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