Table 2

Lists of GO terms ranked according to success rate of miRNA-target prediction by our method.

Best 10


Rank

GO term

Success rate (%)


1

Enzyme linked receptor protein signaling pathway

70.0 (7/10)

2

Negative regulation of cellular metabolic process

66.7 (8/12)

3

Sequence-specific DNA binding

62.5 (10/16)

4

Negative regulation of metabolic process

61.5 (8/13)

5

Response to stress

60.0 (6/10)

Negative regulation of macromolecule metabolic process

60.0 (6/10)

7

Multicellular organismal development

59.4 (19/32)

8

System development

58.3 (14/24)

Anatomical structure development

58.3 (14/24)

10

Regulation of developmental process

57.9 (11/19)


Worst 10


Rank

GO term

Success rate (%)


1

System process

17.6 (3/17)

2

Neurological system process

20.0 (2/10)

Cell cycle

20.0 (3/15)

4

Nucleoplasm

21.4 (3/14)

5

Nuclear lumen

22.2 (4/18)

6

Cell cycle process

23.1 (3/13)

Cell cycle phase

23.1 (3/13)

8

Intrinsic to membrane

25.0 (7/28)

Integral to membrane

25.0 (7/28)

10

Nuclear part

26.3 (5/19)


Success rate of miRNA-target prediction for a GO term x is given by 'number of true positives'/'number of target genes', where GO terms of the numerator and denominator are x.

Fujiwara and Yada BMC Genomics 2013 14(Suppl 2):S3   doi:10.1186/1471-2164-14-S2-S3

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