Partial AUCs and the number of True and False Positives for a range of n vs n comparisons. One hundred random comparisons of n B6 and n D2 mouse striatum samples a performed for six DE methods for n ranging from two to five. For each method and n, (a) partial areas under the ROC curves (partial AUC) are calculated for the regions of FPR less than 0.01 and for the conservative Bonferroni adjusted cut-off of 0.05 the average number of (b) True Positives and (c) False Positive are counted.
Patrick et al. BMC Genomics 2013 14(Suppl 1):S9 doi:10.1186/1471-2164-14-S1-S9