Table 1

Different types of yeast fitness profiles deposited in FitRankDB.

Type of treatment

Type of genome-wide deletion library

Type of fitness profile

Profile #


Chemical effect1

Homozygous deletion strains3

Chemical-genetic (Hom)

918

Chemical effect

Heterozygous deletion strains3

Chemical-genetic (Het)

1,530

Genetic effect2

Homozygous deletion strains

Genetic-genetic (Hom)

12,419


See the details at http://pombe.kaist.ac.kr/fitsearch/statistics/ webcite

1 For example, drug, bioactive compounds or natural crude extracts

2 For example, knock-out, over-expression or mutation of a gene

3 Homozygous (or haploid) and heterozygous (or diploid) deletion collections of S. cerevisiae and S. pombe are commercially available at Open Biosystems (http://www.openbiosystems.com webcite) and Bioneer (http://pombe.bioneer.co.kr webcite), respectively.

Lee et al. BMC Genomics 2013 14(Suppl 1):S6   doi:10.1186/1471-2164-14-S1-S6

Open Data