Table 1

Different types of yeast fitness profiles deposited in FitRankDB.

Type of treatment

Type of genome-wide deletion library

Type of fitness profile

Profile #

Chemical effect1

Homozygous deletion strains3

Chemical-genetic (Hom)


Chemical effect

Heterozygous deletion strains3

Chemical-genetic (Het)


Genetic effect2

Homozygous deletion strains

Genetic-genetic (Hom)


See the details at webcite

1 For example, drug, bioactive compounds or natural crude extracts

2 For example, knock-out, over-expression or mutation of a gene

3 Homozygous (or haploid) and heterozygous (or diploid) deletion collections of S. cerevisiae and S. pombe are commercially available at Open Biosystems ( webcite) and Bioneer ( webcite), respectively.

Lee et al. BMC Genomics 2013 14(Suppl 1):S6   doi:10.1186/1471-2164-14-S1-S6

Open Data