Comparison of T to C conversion ratio between 8-14 mer and 1-7mer target sites in the Hafner et al. PAR-CLIP sequencing data. C: Conserved, N: Nonserved, 7: 7mer seed matching, 8: 8mer seed matching. For example: The CN78 group consists of miRNA target sites within Conserved, Nonconserved UTRs with both 7mer and 8mer matching. In panel J to R, we used only top 102 expressed miRNAs (from Hefner et al.) to calculate the ratios. (A) All miRNAs (B) top 102 expressed miRNAs. Astric marks indicates significant differnece between position 8-14 and 1-7 (p value < 0.05).
Chou et al. BMC Genomics 2013 14(Suppl 1):S2 doi:10.1186/1471-2164-14-S1-S2