JunD expression levels control the production of mature IL-1β in BMDMs and nephritic glomeruli. (A) Western blot of mature IL-1β expression in WKY, WKY.LCrgn2, LEW and LEW.WCrgn2 BMDMs primed with LPS and stimulated with ATP. The result of 3 independent experiments is demonstrated alongside β-actin loading control. ELISAs for IL-1β in LPS primed and ATP activated BMDMs (B) and in nephritic glomeruli (C). **P<0.01 statistically significantly different to WKY using a one way-ANOVA with Bonferonni’s post-tests.
Hull et al. BMC Genomics 2013 14:92 doi:10.1186/1471-2164-14-92