Table 4

Advantages and disadvantages of sample type as RNA source
RNA source Advantages Disadvantages
Mammary tissue Can isolate specific cells Invasive
Milk cells Non-invasive Heterogeneous cell population
Epithelial cell signature Some dying cells
Relatively stable RNA Sensitive to infection, inflammation
Milk fat Non-invasive RNA vulnerable to degradation
Epithelial cell signature
No/low stromal or immune cell signature

Lemay et al.

Lemay et al. BMC Genomics 2013 14:872   doi:10.1186/1471-2164-14-872

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