Table 5

Differential expression of RNA transcripts as detected by a tiled oligonucleotide microarray
Transcript No. Probes Position Size cds Strand* 1121/01 2451/01 1307/01 CDS Product SNP
T1 3 303138-303295 157 Mb0258/nirB A 3↑ nitrite reductase (large sub-unit)
T2 5 303260-303515 255 Mb0258/nirB S 5↑ nitrite reductase (large sub-unit) sSNP at 303227; C-T in 1307/01 only
T3 2 1105085-1105193 108 Mb1014 A 3↑ 3↑ probable adhesion component of ABC transporter
T4 2 1105158-1105315 157 Mb1014 A 3↑ 3↑ probable adhesion component of ABC transporter
T5 3 1105158-1105315 157 Mb1014 S 3↑ 3↑ probable adhesion component of ABC transporter
T6 5 1778876-1779131 255 Mb1618c A 9↑ possible secreted lipase sSNP at 1778879; C-T in 1121/01 only
T7 2 1840174-1840282 108 Mb1672c S 4↓ hypothetical protein
T8 3 1932158-1932315 157 tRNA-Pro S 3↑ proline tRNA
T9 5 1932452-1932707 255 Mb1749c S 4↑ toxin component of toxin-antitoxin system nSNP at 1932704; C-T (G to D) in 1307/01 only
T10 5 1932746-1933075 329 Mb1750c S 7↑ anti-toxin component of toxin-antitoxin system
T11 6 2122959-2123263 304 Mb1914c A 12↑ probable short-chain type dehydrogenase/reductase sSNP at 2122970; C-T in 2451/01 only
T12 2 2324463-2324571 108 Mb2110 S 3↑ hypothetical protein (frame-shifted in 2122/97)
T13 2 2328944-2329052 108 Mb2116c/pepE S 2↓ 3↓ probable dipeptidase
T14 2 2329483-2329591 108 Mb2117 A 10↓ 10↓ 5′-3′ exonuclease nSNP at 2329583; A-G (comp. strand; I to T) in 2451/01 only
T15 3 2868310-2868467 157 Mb2607 A 6↓ 8↓ hp (frame-shifted in 2122/97)
T16 2 2868506-2868614 108 Mb2607 A 7↓ 7↓ hp (frame-shifted in 2122/97) nSNP at 2868616; A-G (stop to W) in 2451/01 and 1307/01;
T17 2 3075740-3075848 108 I 5↑ 6↑
T18 2 3075887-3075995 108 I 5↑ 6↑
T19 2 3076622-3076730 108 I 4↑ 4↑
T20 2 3076769-3076877 108 I 5↑ 5↑
T21 2 3078728-3078836 108 I 6↑ 7↑
T22 2 3079169-3079277 108 I 4↑ 6↑
T23 2 3079903-3080011 108 I 6↑ 7
T24 2 3844577-3844685 108 Mb3509c S 3↑ 3↑ possible acyltransferase (frame-shifted in 2122/97)
T25 6 4155501-4155805 304 Mb3803/echA21 A 5↑ possible enoyl-coA hydratase sSNP at 4155803; C-T (comp. strand) in 2451/01 only
T26 2 4316987-4317095 108 Mb3927c A 3↑ chp (frame-shifted in H37Rv)

Up and down arrows indicate fold up- and downregulation, respectively, and empty cells indicate no change in expression.

*Strand, A indicates antisense, S, sense and I, intergenic.

Golby et al.

Golby et al. BMC Genomics 2013 14:710   doi:10.1186/1471-2164-14-710

Open Data