Dynamical changes of chromosomal interactions between control and E2-treated conditions. Number of gained (i.e. red smooth line, positive value) and lost (i.e. blue smooth line, negative value) interactions between control and E2-treatd conditions are calculated for every 1 Mb region of human genome based on the four types of the strongest chromosomal interactions (i.e. strong differential gain or loss chromosomal intra or inter interactions, Additional file 7).
Wang et al. BMC Genomics 2013 14:70 doi:10.1186/1471-2164-14-70