Functional categorization of lineage-specific genes within zebrafish. Cellular role (A, C) and GO category (B, D) were determined ab initio for orphan genes (A, B) and CTSGs (C, D) by ProtFun and percentage of genes included in each category are given. Cellular role categories are: AAB-amino acid biosynthesis, BOC-biosynthesis of cofactors, CE-cell envelope, CP-cellular processes, CIM-central intermediary metabolism, EM-energy metabolism, FAM-fatty acid metabolism, PP-purines and pyrimidines, RF-regulatory functions, RAT-replication and transcription, T-translation, TAB-transport and binding. GO categories are: ST-signal transducer, R-receptor, H-hormone, SP-structural protein, T-transporter, IC-ion channel, VGIC-voltage-gated ion channel, CC-cation channel, TR-transcription, TRR-transcription regulation, SR-stress response, IR-immune response, GF-growth factor, MIT-metal ions transport.
Yang et al. BMC Genomics 2013 14:65 doi:10.1186/1471-2164-14-65