Table 1

Top concordant regulated miRNAs across different platforms
Index rank hsa-miR Agilent Exiqon Illumina Adj. p-value RT-qPCR
1 hsa-miR-29b 1.54 1.40 2.62 0.00 2.73
2 hsa-miR-29a 1.33 1.36 4.90 0.00 3.37
3 hsa-miR-222 1.58 1.32 1.85 0.00 2.56
4 hsa-miR-132 1.47 1.19 2.46 0.01 2.27
5 hsa-miR-221 1.26 1.31 3.94 0.01 3.31
6 hsa-miR-215 1.20 1.22 3.09 0.18 2.35
7 hsa-miR-21 1.11 1.25 2.02 0.35 2.44
8 hsa-miR-7 1.06 1.12 16.75 0.43 1.63

Rankprod analysis identified 8 miRNAs that were found to be concordantly up-regulated in both microarray platforms (Agilent, Exiqon) and by small RNA-seq sequencing (Illumina). The table shows fold changes for each platform and corresponding Rankprod adjusted p-values. Additionally, these miRNAs were validated by RT-qPCR, with relative expression fold changes provided in the last column.

Llorens et al.

Llorens et al. BMC Genomics 2013 14:371   doi:10.1186/1471-2164-14-371

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