Table 4

Significantly overrepresented functional annotations describing sleep-enhanced transcripts in the lung
Cluster 1
Category Term P-Value Fold Enrichment FDR
SP_PIR_KEYWORDS Carbohydrate metabolism 6.82E-05 7.856 0.089071
Cluster 2
Category Term P-Value Fold Enrichment FDR
SP_PIR_KEYWORDS Glycoprotein 5.49E-04 1.445 0.714887
Cluster 3
Category Term P-Value Fold Enrichment FDR
GOTERM_BP_FAT GO:0006790 Sulfur metabolic process 0.0015 5.604 2.36

Sleep enhanced transcripts demonstrate both significantly increased expression in sleep as compared to sleep deprivation (FDR < 1%) and increasing expression as spontaneous sleep progresses (FDR <1%). Overrepresented functional annotations describing this group of transcripts that met a FDR cutoff of 5% are shown. Clusters describe overlapping gene annotations as determined by the DAVID functional clustering feature.

Anafi et al.

Anafi et al. BMC Genomics 2013 14:362   doi:10.1186/1471-2164-14-362

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