Table 2

Major gene ontology biological process classifications represented by genes differentially expressed between control quarters from cows infected with E. coli (EC24T0) and S. aureus (SA24T0)
Clone accession No. Gene symbol Gene Fold difference
CELLULAR COMPONENT ORGANIZATION AND BIOGENESIS
EC24T0 > SA24T0
AM017607 ARPC5L actin related protein 2/3 complex, subunit 5-like 2.52
CN821828 AGT angiotensinogen 3.73
AM034974 BZW2 basic leucine zipper and W2 domains 2 2.48
BG693016 BTG1 B-cell translocation gene 1, anti-proliferative 2.67
BF076579 BAX BCL2-associated X protein 2.02
AJ818096 CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 2.19
CO888526 EMP1 epithelial membrane protein 1 2.30
CN824732 EIF1 eukaryotic translation initiation factor 1 2.08
CO894798 EIF1B eukaryotic translation initiation factor 1B 2.03
CO888678 EIF3D eukaryotic translation initiation factor 3, subunit D 2.03
AJ691100 EIF4A2 eukaryotic translation initiation factor 4A, isoform 2 2.52
CN823782 GABARAPL1 GABA(A) receptor-associated protein like 1 3.10
AJ818246 HSPD1 heat shock 60 kDa protein 1 2.34
AJ673268 HIST1H2AC histone cluster 1, H2ac 3.30
CO884622 MID1IP1 MID1 interacting protein 1 2.18
AJ819252 MKI67IP MKI67 (FHA domain) interacting nucleolar phosphoprotein 2.29
AJ673531 NDP Norrie disease 3.44
AM037100 NUPR1 nuclear protein 1 2.27
CO888501 PDPK1 3-phosphoinositide dependent protein kinase-1 2.45
AM030492 PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 2.63
CO890613 RAB43 RAB43, member RAS oncogene family 2.29
AJ813402 SETD7 SET domain containing (lysine methyltransferase) 7 2.40
AJ813146 SNRPG small nuclear ribonucleoprotein polypeptide G 2.73
CO886482 SLC3A2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 2.54
CO892251 SLC7A8 solute carrier family 7 (cationic amino acid transporter, y + system), member 8 4.39
CO890843 STOM stomatin 3.65
CO880484 SNTA1 syntrophin, alpha 1 4.49
CO887666 UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A 2.26
SA24T0 > EC24T0
CO889600 AMOT angiomotin 2.12
CO889378 CNN1 calponin 1, basic, smooth muscle 2.49
CN822971 CALR calreticulin 2.36
BF604066 CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 2.43
CO888048 CXCL12 chemokine (C-X-C motif) ligand 12 3.23
CO202183 FEZ1 fasciculation and elongation protein zeta 1 3.13
CO873026 FLNA filamin A, alpha 2.31
AJ692384 GLMN glomulin, FKBP associated protein 2.01
CN824202 GSK3B glycogen synthase kinase 3 beta 2.02
CO887046 LRRC4C leucine rich repeat containing 4C 2.92
CO872154 LASP1 LIM and SH3 protein 1 2.09
AM025652 MRPL32 mitochondrial ribosomal protein L32 2.06
CO893984 MYO9B myosin IXB 4.03
CO889939 MYH11 myosin, heavy chain 11, smooth muscle 2.70
AM018723 PIGR polymeric immunoglobulin receptor 2.03
AJ687977 SEC24D SEC24 related gene family, member D 2.02
CO894656 SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 3.32
CO876411 THY1 Thy-1 cell surface antigen 2.10
pTGFB1* TGFB1 transforming growth factor beta 1 2.32
AJ814326 B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase polypeptide 1 2.45
AM033343 VIM vimentin 2.36
CO880794 WIPF1 WAS/WASL interacting protein family, member 1 2.34
RESPONSE TO STRESS
EC24T0 > SA24T0
AM006216 ATF4 activating transcription factor 4 2.07
CN821828 AGT angiotensinogen 3.73
BF076579 BAX BCL2-associated X protein 2.02
AJ818096 CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 2.19
BF606419 CXCL2 chemokine (C-X-C motif) ligand 2 2.03
CO889145 CSDA cold shock domain protein A 3.16
CN824732 EIF1 eukaryotic translation initiation factor 1 2.08
CO892245 GADD45G growth arrest and DNA-damage-inducible, gamma 2.91
AJ818246 HSPD1 heat shock 60 kDa protein 1 2.34
CN824191 HSP90AB1 heat shock protein 90 kDa alpha (cytosolic), class B member 1 2.25
AJ818172 HIF1A hypoxia-inducible factor 1, alpha subunit 2.41
AM013900 LBP lipopolysaccharide binding protein 2.79
CO888501 PDPK1 3-phosphoinositide dependent protein kinase-1 2.45
CN823413 SEPP1 selenoprotein P, plasma, 1 2.12
CO886480 STAT3 signal transducer and activator of transcription 3 2.25
AM025615 TRIB3 tribbles homolog 3 3.02
SA24T0 > EC24T0
CO888048 CXCL12 chemokine (C-X-C motif) ligand 12 3.23
CO883340 CFD complement factor D 2.31
CN824202 GSK3B glycogen synthase kinase 3 beta 2.02
AJ820250 IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 3.36
CO886661 RECQL5 RecQ protein-like 5 2.60
CO887968 TYMS thymidylate synthetase 3.35
AJ695939 TFPI2 tissue factor pathway inhibitor 2 2.03
pTGFB1* TGFB1 transforming growth factor beta 1 2.32
AJ814326 B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase polypeptide 1 2.45
DEATH
EC24T0 > SA24T0
CN821828 AGT angiotensinogen 3.73
BG693016 BTG1 B-cell translocation gene 1, anti-proliferative 2.67
BF076579 BAX BCL2-associated X protein 2.02
AJ818096 CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 2.19
CO888526 EMP1 epithelial membrane protein 1 2.30
CO892245 GADD45G growth arrest and DNA-damage-inducible, gamma 2.91
AJ818246 HSPD1 heat shock 60 kDa protein 1 2.34
AM037100 NUPR1 nuclear protein 1 2.27
CO883017 PHLPP PH domain and leucine rich repeat protein phosphatise 2.26
CO885391 TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 3.05
AM025615 TRIB3 tribbles homolog 3 3.02
SA24T0 > EC24T0
CN822971 CALR calreticulin 2.36
BF604066 CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 2.43
pCSF2* CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.57
CN824202 GSK3B glycogen synthase kinase 3 beta 2.02
pTGFB1* TGFB1 transforming growth factor beta 1 2.32
AJ814326 B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase polypeptide 1 2.45
CELL ACTIVATION
EC24T0 > SA24T0
CN821828 AGT angiotensinogen 3.73
BF076579 BAX BCL2-associated X protein 2.02
AJ818096 CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 2.19
SA24T0 > EC24T0
BF604066 CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 2.43
pCSF2* CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.57
AJ692384 GLMN glomulin, FKBP associated protein 2.01
CO876411 THY1 Thy-1 cell surface antigen 2.10
pTGFB1* TGFB1 transforming growth factor beta 1 2.32

A single accession number is listed for genes represented by multiple clones. Average fold differences were calculated when multiple clones represented a transcript. * pTGFB1 and pCSF2 are amplicons generated specifically for the Bov20K cDNA microarray.

Jensen et al.

Jensen et al. BMC Genomics 2013 14:36   doi:10.1186/1471-2164-14-36

Open Data