Changes in miRNA total regulatory load on mRNAs and total expression at indicated time points posthepatectomy compared to quiescent liver. (A) Sixteen miRNAs were found to have altered levels of RISC-loading during the time course of the experiment. (FDR < = 20%). miR-192-5p has the same seed sequence as mir-215-5p so was included for comparison. (B) The total expression of 16 of these miRNAs was measured using taqMan qRT-PCR at indicated times after partial hepatectomy relative to quiescent liver. N = 2 samples. Significance was calculated by ANOVA. Levels are normalized to quiescent liver for display purposes. Red is lower, yellow-white is higher. A taqMan probe was not available for miR-5620 and was therefore not analyzed.
Schug et al. BMC Genomics 2013 14:264 doi:10.1186/1471-2164-14-264