Table 3

Genes identified by SSH with P. berghei orthologs showing destabilization in the absence of DOZI and CITH
P. falciparum gene ID P Protein Predicted feature MW P. berghei ortholog gene ID DOZI CITH
PF3D7_1011800 74 QF122 antigen KH domain type 1, RNA binding 131.6 PBANKA_121020 1.4 1.1
PF3D7_0724900 0 kinesin-like protein 222.6 PBANKA_062240 2.4 1.2
PF3D7_1033800 0 plasmepsin VII SP, 1 TM, aspartyl protease 52.3 PBANKA_051760 2.1 1.3
PF3D7_1316700 0 conserved Plasmodium protein SP 73.4 PBANKA_141520 2.1 1.4
PF3D7_1321000 0 conserved Plasmodium protein 80.6 PBANKA_141930 1.8 1.6
PF3D7_0303900 19 conserved Plasmodium protein SP, phosphatidyl-ethanolamine-binding protein PEBP domain 23.2 PBANKA_040250 2.2 1.8
PF3D7_1103500 0 CPW-WPC family protein SP, CPW-WPC domain 67.3 PBANKA_094340 1.3 2.3
PF3D7_1115200 0 SET domain protein, SET7 Chromatin regulator 94.3 PBANKA_093250 2.5 2.3
PF3D7_1207700 0 blood stage antigen 41–3 precursor SP 43.4 PBANKA_060620 2.5 2.8
PF3D7_0904200 1 conserved Plasmodium protein SP, 1 TM 34 PBANKA_041720 1.9 3.2
PF3D7_1362600 0 conserved Plasmodium protein Interacts with splicing factor 3B subunit 2 32.1 PBANKA_113860 3.4 3.5

P, total number of peptides identified in P. falciparum and P. berghei gametocytes [9,12,13,22]; DOZI and CITH, log2 values of transcript abundance WT compared to DOZI-KO, or WT compared to CITH KO [20].

Ngwa et al.

Ngwa et al. BMC Genomics 2013 14:256   doi:10.1186/1471-2164-14-256

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