An illustration of our main results. Figure legend text (a) Previous analyses (e.g., [9,17,35]) of the yeast eQTL dataset reported eQTL hotspots, a module of multiple genes controlled by the same genomic locus. (b) In our GFlasso analysis of the same dataset, we not only found eQTL hotspots, but also discovered multiple contributing eQTL hotspots, where the same module of multiple genes is associated with multiple eQTL hotspots. This figure was created using GenAMap [].
Curtis et al. BMC Genomics 2013 14:196 doi:10.1186/1471-2164-14-196