Figure 5.

Functional analysis of genes correlating with agonistic and antagonistic miRNA clusters. (A) Heat maps displaying nonhierarchical unsupervised cluster analyses of the sPCC values derived by comparing the expression of 10 agonistic and 2 antagonistic miRNAs with the combined genes of the 6 oncogenic signatures listed in Figure 4A (data are found in Additional file 13: Table S12). (B) IPA network analysis of the combined genes (from the 6 oncogenic gene signatures) that positively correlated with the agonistic miRNAs (upper panel) or antagonistic miRNAs (lower panel). (C) DAVID gene ontology analysis of the same genes analyzed in B. Lists of genes used for these analyses can be found in Additional file 11: Table S10.

Hua et al. BMC Genomics 2013 14:179   doi:10.1186/1471-2164-14-179
Download authors' original image