Table 2

RXE across paralogs
Human brain Human liver Human lymphoblast 45, Xm Human lymphoblast 45, Xp Human lymphoblast
cis-paralogs 2.57 (41, 30) 0.18 (31, 28) 0.51 (13, 18) 0.79 (14, 17) 0.24 (38, 31)
trans-paralogs −0.64 (76, 43)* 0 (69, 40) 0.20 (56, 31) −0.55 (61, 63) −0.06 (77, 44)
all paralogs 0.49 (106, 65) 0.03 (93, 60) 0.14 (66, 43) −0.15 (68, 46) 0.19 (104, 70)
non-paralogs −0.18 (415, 546)* −0.5 (378, 520)* −0.32 (269, 393)* −0.38 (272, 412)* −0.73 (400, 559)*

Relative X-chromosome expression values across both cis and trans-paralogs for five human libraries. Cis-paralogs show an increased RXE compared to trans-paralogs and non-paralogous elements. Bolded value identifies case where X chromosome and autosome expression are significantly different from each other (p < 0.05, Kolmogorov-Smirnov test, with bootstrapping −1000 replicates). Cross indicates X chromosome expression greater than autosomes, while asterisk indicates X chromosome expression less than autosomes.

Jue et al.

Jue et al. BMC Genomics 2013 14:150   doi:10.1186/1471-2164-14-150

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