Table 4

Relative mRNA expression of experimental treatments at 3 hr for genes involved in adherin junctions, tight junctions, or angiogenesis
NCBI gene symbol AMPH compared to control EIH compared to control AMPH compared to EIH
MAV Choroid plexus MAV Choroid plexus MAV Choroid plexus
Ocln 0.36 1.17a 0.67 1.21a 0.54 0.96a
Cldn1 0.86 1.04a 0.97 1.18a 0.88 0.88a
Cldn3 1.22 1.02 0.99 0.88 1.23 1.16
Cldn4 1.50 0.77 1.60 1.00 0.94 0.78
Cldn5 0.41a 0.32 0.59a 0.48 0.69a 0.66
Cldn11 0.88 0.48 0.81 0.77 1.09 0.62
Magi2 0.90 0.51 1.16 0.88 0.77 0.58
Magi3 0.74 1.01 1.08 1.07 0.69 0.94
Esam 2.07b 1.92 1.14 1.85 1.85a 1.04
F11r (Jam1) 0.73a 1.09 0.69a 0.94 1.06a 1.16
Jam2 0.67 0.97 0.96 0.92 0.70 1.05
Jam3 0.77 0.77 0.84 0.71 0.91 1.09
Cdh5 0.92 0.87 1.03 1.41 0.90 0.62
Aqp4 0.76a 0.52 1.05b 0.66 0.73a 0.78
Slc2a1 1.39 0.82 1.13 1.04 1.24 0.79
Angpt2 1.02a 1.12 1.02a 1.21 1.00a 0.66
Tek 0.43 0.88 0.62 1.38 0.69 0.64
Ctnnb1 1.29 0.74 0.83 0.68 1.56 1.09
Pdgfrb 0.60 0.60 0.86 0.95 0.70 0.63
Sox18 0.33a 0.70 0.67a 0.70 0.50a 1.01
Agrn 0.70 0.81 0.77 0.70 0.91 1.15

Bold text indicates genes that were significantly differentially expressed (FDR = 0.10) between treatment comparisons.

a Array expression results were confirmed with RT-PCR.

b Array expression results were not confirmed with RT-PCR.

Bowyer et al.

Bowyer et al. BMC Genomics 2013 14:147   doi:10.1186/1471-2164-14-147

Open Data