Open Access Research article

Global analysis of transcriptional regulators in Staphylococcus aureus

Jose Antonio Ibarra13*, Ernesto Pérez-Rueda2*, Ronan K Carroll1 and Lindsey N Shaw1

Author Affiliations

1 Department of Cell Biology, Microbiology and Molecular Biology, University of South Florida, 4202 East Fowler Avenue, ISA 2015, Tampa, FL, 33620-5150, USA

2 Departamento de Ingeniería Celular y Biocatálisis, Instituto de Biotecnologia UNAM, Av Universidad 2001, Cuernavaca, Morelos, CP 62210, Mexico

3 Present address: Departamento de Microbiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Prol. De Carpio y Plan de Ayala. Col. Sto. Tomás, México, DF, CP 11340, Mexico

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BMC Genomics 2013, 14:126  doi:10.1186/1471-2164-14-126

Published: 26 February 2013

Additional files

Additional file 1: Table S1:

S. aureus USA300 TFs conserved in eubacteria. Groups are defined as: 1, proteins with orthologues in 60–100% of genomes studied; 2, 15-59%; 3, 1–14%; and 4 <1% of genomes. Table S2.S. aureus strains analyzed in this work.

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Additional file 2: Figure S1:

Phylogenetic tree for the MarR-like proteins. Sar and MarR proteins, along with uncharecterized MarR proteins, were aligned using the MgrA crystal (2BV6) structure as a template. Three clades are denoted, see text for details. SarU, SAUSA300_1114 and SAUSA300_2247 exhibit two MgrA-like domains and therefore are shown as duplicated in the tree.

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