The mutation rates for all CpG sites, methylated CpG sites and unmethylated CpG sites. The methylated CpG sites are further categorized into five groups according to their methylation levels. The X-axis includes CpG sites with different methylation levels (Total_CpG: total CpG; mCpG: methylated CpG; H_mCpG: highly methylated CpG (> 80%); HI_mCpG: high-intermediately methylated CpG (60-80%); I_mCpG: intermediately methylated CpG (40-60%); LI_mCpG: low-intermediately methylated CpG (20-40%); L_mCpG: lowly methylated CpG (≤ 20%); unCpG: unmethlated CpG). The Y-axis is the mutation rate that was calculated as the SNP density at CpG sites.
Xia et al. BMC Genomics 2012 13(Suppl 8):S7 doi:10.1186/1471-2164-13-S8-S7