Table 9

Ensemble causal orientation results and comparison with the best performing individual causal orientation methods

ECOLI

YEAST

NOTCH1

RELA


Best individual causal orientation method (AUC)

0.828

0.658

0.926

0.970

Ensemble method (AUC)

0.837

0.822

0.984

0.992

Improvement (AUC)

0.009

0.164

0.058

0.022

Statistical significance of improvement (p-value)

0.3407

<0.0001

0.0062

<0.0001


Bold p-values indicate a statistically significant performance improvement by using an ensemble causal orientation. The p-values were obtained from Delong's test for AUC comparison [45].

Statnikov et al. BMC Genomics 2012 13(Suppl 8):S22   doi:10.1186/1471-2164-13-S8-S22

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