Expression profiles of MAPK signalling pathway as an example of discordant pathway. Expression profiles of MAPK signalling pathway in the two cohort datasets of lung cancer grade are shown. (A) Expression profile of 244 member genes. (B) Pathway expression profiles aggregated by the six methods. In grade 3, the pathway shows an up-regulation in the Dana-Farber cohort but a down-regulation in the Michigan cohort.
Hwang BMC Genomics 2012 13(Suppl 7):S26 doi:10.1186/1471-2164-13-S7-S26