Figure 1.

Support and weighted support. A schematic example of classification of genetic variation profiles and computation of their supports. Point mutations 1 and 4 are essential, mutation 2 is conflict and mutation 3 is neutral. Light blue circles mark nodes which appear in the definition of weighted support. These are nodes the highest parental nodes (for the leaf nodes corresponding to drug-resistant strains), that their subtrees do not contain any drug-susceptible strains in leaves. The scores (a) support and (b) weighted support are assigned to these mutations. For this drug-resistance profile, the ratio αv equals <a onClick="popup('','MathML',630,470);return false;" target="_blank" href="">View MathML</a>.

Wozniak et al. BMC Genomics 2012 13(Suppl 7):S23   doi:10.1186/1471-2164-13-S7-S23