Interactions between LPKC and withaferin A drawn by Ligplot. Figure shows the changes in interactions and conformation of bound withaferin A with LPKC during 10ns MD simulations. A) Change in interaction profile of withaferin A-LPKC complex during the MD simulations. B) Superimposed withaferin A-LPKC complex structures before the simulation (red) and after the simulation (green). Blue circles specify the regions of conformational change in withaferin A structure.
Grover et al. BMC Genomics 2012 13(Suppl 7):S20 doi:10.1186/1471-2164-13-S7-S20