Table 2

Comparison of miRNA-centric μ and gene-centric ρ measuresa

GO terms

ρi

ρj

ρk

ρl

p-valueρ (rank)


μi

μj

μk

μl

p-valueμ (rank)

GO:0033137, negative regulation

3

7485

0

10148

0.0765 (299)

of peptidyl-serine phosphorylation

6

0

282

265

0.0195 (14)

GO:0006474, N-terminal protein

3

7485

0

10148

0.0765 (299)

amino acid acetylation

6

0

320

227

0.0412 (28)

GO:0008054, cyclin catabolic

2

7486

2

10146

0.5668 (1842)

process

6

0

322

225

0.0427 (32)


GO:0031047, gene silencing by RNA

19

7460

6

10142

0.0006 (25)

6

0

537

10

0.8958 (2566)

GO:0030335, positive regulation of cell migration

34

7454

16

10132

2.31e-04 (18)

6

0

545

2

0.9783 (2879)

GO:0045944, positive regulation of

150

7338

112

10036

8.62e-07 (4)

transcription from RNA polymerase II promoter

6

0

546

1

0.9891 (2923)


GO:0006956, complement

1

7487

0

10148

0.4246 (1251)

activation

2

4

3

544

0.0010 (1)

GO:0060022, hard palate

1

7487

0

10148

0.4246 (1251)

development

4

2

85

462

0.0073 (3)

GO:0060123, regulation of growth

1

7487

0

10148

0.4246 (1251)

hormone secretion

4

2

87

460

0.0079 (4)

GO:0032926, negative regulation

3

7485

0

10148

0.07652 (286)

of activin receptor signaling pathway

5

1

226

321

0.0437 (35)

GO:0015936, coenzyme A

1

7487

1

10147

0.6689 (2086)

metabolic process

5

1

160

387

0.0102 (5)


a The 'breast/up-regulated' miRNA cluster data from Volinia et al. (2006) using the target variation #6 (see Table 1) was used.

Lee et al. BMC Genomics 2012 13(Suppl 7):S17   doi:10.1186/1471-2164-13-S7-S17

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