GeneGo pathway (A) and disease (B) analyses indicated cancer-related genes were enriched. A. Eight out of 10 pathways enriched are related to cancer. Among these, Pathways 1, 3, and 4 are also related to immune responses. Pathway 2 and 5 are involved with cytoskeleton remodeling. Pathway 6 is transition and termination of DNA replication. Pathway 8 and 9 are adhesion related. B. Out of top 10 most enriched GeneGO disease categories, 7 are cancer related (1-3, 5, 6, 8, and 10). The more significant it is the longer the orange bar. A bar of 15 in length corresponds to a p-value of 1e-15.
Wu et al. BMC Genomics 2012 13(Suppl 7):S12 doi:10.1186/1471-2164-13-S7-S12