Table 2

Statistical results for modulator-TF-target Interaction

ERα genomic

ERα non-genomic


Classification

a2

b1

b2

# of unique M/T

# of connection

FDR (%)

# of unique M/T

# of connection

FDR (%)


1

TF (Ind. Activator)

0

+

0

-

-

-

-

-

-

2

TF (Ind. Repressor)

0

-

0

-

-

-

-

-

-

3

TF (Ind. Activator) and M (Ind. Activator)

+

+

0

58/21

67

34.870

367/2590

6447

1.906

4

TF (Ind. Repressor) and M (Ind. Activator)

+

-

0

0/0

0

NA

0/0

0

NA

5

TF (Ind. Activator) and M (Ind. Repressor)

-

+

0

36/14

40

16.688

306/1035

3230

~ 0

6

TF (Ind. Repressor) and M (Ind. Repressor)

-

-

0

0/0

0

NA

144/88

349

~ 0

7

TF (Activator) and M (Agonist)

0

+

+

185/21

307

14.133

419/2372

71465

0.587

8

TF (Activator) and M (Antagonist)

0

+

-

282/47

908

3.676

470/4875

71166

0.824

9

TF (Repressor) and M (Antagonist)

0

-

+

94/2

96

0

258/206

5125

1.289

10

TF (Repressor) and M (Agonist)

0

-

-

0/0

0

NA

0/0

0

NA

11

TF (Activator) and M (Agonist & Ind. Activator)

+

+

+

0/0

0

NA

0/0

0

NA

12

TF (Activator) and M (Antagonist & Ind. Activator)

+

+

-

284/51

849

1.572

477/5204

78213

0.206

13

TF (Repressor) and M (Antagonist & Ind. Activator)

+

-

+

0/0

0

NA

0/0

0

NA

14

TF (Repressor) and M (Agonist & Ind. Activator)

+

-

-

0/0

0

NA

0/0

0

NA

15

TF (Activator) and M (Agonist & Ind. Repressor)

-

+

+

272/22

934

1.072

432/2171

51064

0.244

16

TF (Activator) and M (Antagonist & Ind. Repressor)

-

+

-

0/0

0

NA

0/0

0

NA

17

TF (Repressor) and M (Antagonist & Ind. Repressor)

-

-

+

23/2

26

12.837

332/442

8152

~ 0

18

TF (Repressor) and M (Agonist & Ind. Repressor)

-

-

-

0/0

0

NA

0/0

0

NA

19

M (Ind. Activator)

+

0

0

-

-

-

-

-

-

20

M (Ind. Repressor)

-

0

0

-

-

-

-

-

-

21

M (Activator Agonist)

0

0

+

261/37

835

4.797

418/3619

118241

0.479

22

M (Repressor Agonist)

0

0

-

42/8

65

15.404

213/977

5546

1.709

23

M (Activator Agonist & Ind. Activator)

+

0

+

0/0

0

NA

0/0

0

NA

24

M (Repressor Agonist & Ind. Activator)

+

0

-

23/9

34

19.633

354/1453

6119

0.951

25

M (Activator Agonist & Ind. Repressor)

-

0

+

277/40

638

2.093

440/3852

80644

0.336

26

M (Repressor Agonist & Ind. Repressor)

-

0

-

0/0

0

NA

0/0

0

NA

27

No Function

0

0

0

-

-

-

-

-

-


Wu et al. BMC Genomics 2012 13(Suppl 6):S6   doi:10.1186/1471-2164-13-S6-S6

Open Data