Table 5

Performance for optimizing the combination of four drugs in the presence of noise.

Noise level

Search type

Performance metric

Gur Game (simultaneous)

Gur Game (sequential)

Previous search algorithm [11](α = 1)

ARU algorithm (proposed) (α = 1)


f4a(x)

(2%)

A

success rate unique comb.

21%

13%

96%

98%

798.9

711.7

393.9

327.4

B

success rate iterations

21%

12%

96%

97%

941.9

1032.1

558.3

452.3


(5%)

A

success rate unique comb.

21%

14%

90%

95%

816.3

653.6

473.1

398.3

B

success rate iterations

21%

13%

90%

95%

895.6

1022.9

675.4

581.2


(8%)

A

success rate unique comb.

24%

14%

85%

95%

858.7

681.6

505.7

433.6

B

success rate iterations

23%

13%

84%

92%

997.1

1008.9

720.8

648.5


f4b(x)

(2%)

A

success rate unique comb.

62%

41%

100%

100%

634.5

523.1

138.0

103.1

B

success rate iterations

51%

26%

100%

100%

932.4

903.0

236.9

182.8


(5%)

A

success rate unique comb.

75%

68%

100%

100%

610..2

468.0

231.1

150.9

B

success rate iterations

50%

25%

100%

100%

855.9

921.2

411.0

258.8


(8%)

A

success rate unique comb.

86%

82%

98%

100%

525.8

430.1

314.2

215.9

B

success rate iterations

50%

24%

94%

100%

835.3

979.2

602.0

393.8


Kim and Yoon BMC Genomics 2012 13(Suppl 6):S12   doi:10.1186/1471-2164-13-S6-S12

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