Resolution:
standard / ## Figure 3.
Example showing how the inclusion of other parameters can improve sensitivity in a
decoy DB approach. For a FDR = 0, just three identifications can be retrieved when applying Xcorr thresholds.
The addition of ΔCallows threshold combinations resulting in five identifications (rectangles and ellipses).
(a) Textual representation. (b) Graphical representation (Δ_{n }Cvs. Xcorr), where crosses represent decoy PSMs and circles denote normal PSMs. We
added here the green curve in (b) to show that a non-linear decision boundary is expected
to further enhance sensitivity in such analysis.
_{n }Cerqueira |