Table 1

Mutation counts for colon cancer

Total patients

100


Total mutations

21,572


Total nonsynonymous SNVs

17,174 (79.6%)


Total frameshift insertions

2,527 (11.7%)


Total nonframeshift insertions

239 (1.1%)


Total frameshift deletions

5 (0.0%)


Total nonframeshift deletions

0 (0.0%)


Total stop-loss SNVs

33 (0.2%)


Total stop-gain SNVs

1,594 (7.4%)


Mutations in domain regions

10,647 (49.4%)


Average mutations per patient

216 (± 552)


Number of mutations per patient

21-4,880


Summary of somatic mutations occurring in the exomes of 100 colon cancer tumor samples. Synonymous SNVs and variants present in dbSNP (release 130) were removed due to their low likelihood of being driver mutations.

Nehrt et al. BMC Genomics 2012 13(Suppl 4):S9   doi:10.1186/1471-2164-13-S4-S9

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