Table 1

Comparison of the variation annealing (Proposed) and EM algorithm (EM) based on the proposed model

(a)


# of time points

50

25


# TP

# FP

PRE

# TP

# FP

PRE

Proposed

295.9

41.7

0.88

238.4

71.6

0.77

EM

294.9

119.2

0.71

196.8

66.9

0.75


(b)


# of time points

50

25


# TP

# FP

PRE

# TP

# FP

PRE

Proposed

39.8

13.2

0.75

23.4

20.8

0.53

EM

39.9

39.4

0.5

11.5

10.0

0.53


(a) The number of true positives (# TP) and false positives (# FP) of estimated regulations in two network models by the proposed approach and EM for equally spaced time series data. PRE denotes the precision of the results. Regulations in two networks are 305 in total. (b) The number of true positives (# TP) and false positives (# FP) of changes on regulations between two network models estimated by the proposed approach and EM for equally spaced time series data. The regulations changed in two networks are in total 47.

Kojima et al. BMC Genomics 2012 13(Suppl 1):S6   doi:10.1186/1471-2164-13-S1-S6

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