(a) Parasites can be located in close proximity to each other in manners that lead to segmentation errors. (b) Bipartite graph describing the splitting of a blob (containing two parasites) into two blobs containing a single parasite each. (c) Group of four parasites, erroneously assigned to a single blob after segmentation. Analysis of the various combinations of intensity-boxes leads to the recovery of one of the four parasites from this blob.
Lee et al. BMC Genomics 2012 13(Suppl 1):S4 doi:10.1186/1471-2164-13-S1-S4