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This article is part of the supplement: Selected articles from the Tenth Asia Pacific Bioinformatics Conference (APBC 2012)

Open Access Proceedings

Detection of interacting transcription factors in human tissues using predicted DNA binding affinity

Alena Myšičková* and Martin Vingron

Author Affiliations

Max Planck Institute for Molecular Genetics, Ihnestr. 73, 14195 Berlin, Germany

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BMC Genomics 2012, 13(Suppl 1):S2  doi:10.1186/1471-2164-13-S1-S2

Published: 17 January 2012

Additional files

Additional file 1:

Table of all predicted interactions by tissue. Table with all predicted tissue-specific TF pairs with their motif similarity, p-value from the 3-way-contingency table test, shared co-factors and PPI database evidence.

Format: XLS Size: 165KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 2:

Smooth scatterplot of p-values of the 3-way contingency table test in liver and motif similarity measure. Logarithm of the p-values of the 3-way contingency table test for TF pairs in liver (vertical axis) vs. motif similarity measure Smax (horizontal axis). Red points and orange triangles denote experimentally shown PPIs and trios with a known interacting co-factor, respectively.

Format: PDF Size: 830KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data