PCA of gene features grouped by MSL binding and expression status. Results of PCA of gene feature sequences of genes that are expressed/unexpressed and strongly/weakly bound by MSL. Chromosomes colour-coded, and gene features indicated by symbols as follows: green = X, magenta = 3R, brown = 2R, blue = 3L, yellow = 2L; O = all genes, Δ = expressed genes (EXP), ∇ = unexpressed genes (UN-EXP), + = MSL strongly bound genes (MSL-SB), × = MSL weakly bound genes (MSL-WB), Δ = expressed MSL strongly bound genes (EXP-MSL-SB), ∇ = expressed MSL weakly bound genes (EXP-MSL-WB). (A), (B), (C), (D), (E) and (F) show 1st vs 2nd component score plots (R2cum = 0.657, 0.517, 0.732, 0.872, 0.577 and 0.761, respectively) of the AT-normalized 2-6 mer promoter, 5' UTR, coding sequence, intron, 3' UTR and intergenic sequence analyses, respectively.
Philip et al. BMC Genomics 2012 13:97 doi:10.1186/1471-2164-13-97