Open Access Research article

Genome sequencing of ovine isolates of Mycobacterium avium subspecies paratuberculosis offers insights into host association

John P Bannantine1*, Chia-wei Wu2, Chungyi Hsu2, Shiguo Zhou3, David C Schwartz3, Darrell O Bayles1, Michael L Paustian1, David P Alt1, Srinand Sreevatsan4, Vivek Kapur5 and Adel M Talaat26*

Author Affiliations

1 National Animal Disease Center, USDA-Agricultural Research Service, Ames, Iowa, USA

2 The Laboratory of Bacterial Genomics, Department of Pathobiological Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA

3 Laboratory for Molecular and Computational Genomics, Department of Chemistry and Laboratory of Genetics, UW Biotechnology Center, University of Wisconsin-Madison, Madison, Wisconsin, USA

4 Department of Veterinary Population Medicine and Department of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, Minnesota, USA

5 Department of Veterinary and Biomedical Sciences and Huck Institutes of the Life Sciences, Penn State University, University Park, Pennsylvania, USA

6 Department of Food Hygiene, Cairo University, Cairo, Egypt

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BMC Genomics 2012, 13:89  doi:10.1186/1471-2164-13-89

Published: 12 March 2012

Additional files

Additional file 1:

Table S1. PSORT analysis of MAP S397 genes to determine their localization.

Format: XLSX Size: 191KB Download file

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Additional file 2:

Table S2. A list of 184 genomic DNA scaffolds of MAP S397 genome.

Format: XLSX Size: 70KB Download file

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Additional file 3:

Table S3. Synteny of annotated genes between MAP K-10 and MAP S397 genomes.

Format: XLSX Size: 127KB Download file

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Additional file 4:

Table S4. MAP S397 genes that are absent in MAP K-10.

Format: XLSX Size: 34KB Download file

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Additional file 5:

Table S5. MAP K-10 genes that are absent in MAP S397. All supplemental tables are in Excel format.

Format: XLS Size: 58KB Download file

This file can be viewed with: Microsoft Excel Viewer

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Additional file 6:

Figure S1. An overview alignment of MAP S397 scaffold assembly and BsiWI restriction fragments.

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This file can be viewed with: Adobe Acrobat Reader

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