Table 3

Effect of a chronic Western diet on the expression of genes related to cholesterol metabolism in the livera

Symbol

Gene name

FC

p-value


Cyp51

Cytochrome P450, family 51

1.80 ± 0.28

0.056


Dhcr7

7-dehydrocholesterol reductase

1.72 ± 0.23

0.025


Hmgcr

3-hydroxy-3-methylglutaryl-Coenzyme A reductase

2.23 ± 0.48

0.033


Pmvk

Phosphomevalonate kinase

1.22 ± 0.16

0.378


Srebp-2

Sterol regulatory element binding factor 2

1.37 ± 0.08

0.009


a Abbreviations: FC fold change (Western diet vs. control)

Desmarchelier et al. BMC Genomics 2012 13:84   doi:10.1186/1471-2164-13-84

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