Table 6

Different Expression Levels Among Members of Common Gene Families Expressed in the SAE1

Category

Gene name

Gene symbol

Median expression level (RPKM)


Cilia

tubulin, alpha

TUBA1A

341.7

TUBA1B

162.6

TUBA1C

120.5

tubulin, beta

TUBB2A

38.7

TUBB2B

23.3

TUBB4

14.8

Annexin (signal

transduction)

annexin A2

ANXA2

362.1

ANXA2P2

292.3

ANXA2P1

42.6

ANXA2P3

26.1

Glutathione

S-transferase alpha

glutathione S-transferase alpha

GSTA1

248.9

GSTA2

143.9

GSTA3

15.9

GSTA5

9.3

Glutathione

S-transferase mu

glutathione S-transferase mu

GSTM2

35.9

GSTM1

20.8

GSTM4

8.8

Sulfotransferase -

phenol preferring

sulfotransferase family, cytosolic, 1A, phenol-preferring

SULT1A1

25.7

SULT1A4

14.6

SULT1A3

10.3

SULT1A2

5.4

SLX1A-SULT1A3

SLX1B-SULT1A4

Amylase

amylase, alpha

AMY1A

43.4

AMY1B

18.6

AMY1C

15.1

AMY2B

13.8

AMY2A

7.3

Polarity/left right

signaling

NODAL modulator

NOMO2

22.4

NOMO1

16.0

NOMO3

14.3

Metallothionein

metallothionein

MT1E

33.2

MT1L

2.4

MT1M

1.1

MT1JP

P450

cytochrome P450, family 2, subfamily A, polypeptides

CYP2A13

17.2

CYP2A6

4.2

CYP2A7

1.4

Aldo-keto reductase

aldo-keto reductase family 7

AKR7A2

34.1

AKR7A3

3.0

AKR7L

1.5

AKR7A2P1

Aldehyde

dehydrogenase

alcohol dehydrogenase

ADH1C

52.2

ADH1B

4.3

ADH1A

2.6

Short chain

dehydrogenase

dehydrogenase/reductase

DHRS9

68.4

MUC20

27.5

VPS53

4.0

SMU1

3.9

FAM153B

0.4

LEP

0.0


1 List of gene families identified using BLAST with ≥ 90% identity and alignment lengths of at least 50% in both sequences. They were categorized by gene family and sorted in descending order within each category by median expression level for n = 5 nonsmokers.

Hackett et al. BMC Genomics 2012 13:82   doi:10.1186/1471-2164-13-82

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