Table 3 |
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|
Highly Expressed SAE-enriched Transcription Factors1 |
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|
Category |
Gene symbol |
Gene title |
Median expression level (RPKM) |
|
|
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|
Basic helix-loop -helix |
ATF6B |
activating transcription factor 6 beta |
26.4 |
|
BHLHE40 |
basic helix-loop-helix family, member e40 |
16.2 |
|
|
RFX3 |
regulatory factor X, 3 (influences HLA class II expression) |
15.6 |
|
|
HES6 |
hairy and enhancer of split 6 (Drosophila) |
13.6 |
|
|
FOXC1 |
forkhead box C1 |
9.3 |
|
|
CEBPA |
CCAAT/enhancer binding protein (C/EBP), alpha |
9.1 |
|
|
HEY1 |
hairy/enhancer-of-split related with YRPW motif 1 |
9.1 |
|
|
Zinc finger |
TRIM29 |
tripartite motif-containing 29 |
77.3 |
|
KLF5 |
kruppel-like factor 5 (intestinal) |
42.0 |
|
|
RREB1 |
ras responsive element binding protein 1 |
7.2 |
|
|
KLF4 |
kruppel-like factor 4 (gut) |
7.1 |
|
|
Helix-turn-helix |
FOXJ1 |
forkhead box J1 |
363.1 |
|
ELF3 |
E74-like factor 3 (ets domain transcription factor, epithelial-specific) |
170.1 |
|
|
FOXA1 |
forkhead box A1 |
62.6 |
|
|
EHF |
ets homologous factor |
39.1 |
|
|
TBX1 |
T-box 1 |
19.7 |
|
|
SATB1 |
SATB homeobox 1 |
19.3 |
|
|
MYB |
v-myb myeloblastosis viral oncogene homolog (avian) |
15.9 |
|
|
SIX2 |
SIX homeobox 2 |
13.9 |
|
|
NKX2-1 |
NK2 homeobox 1 |
11.6 |
|
|
PHTF1 |
putative homeodomain transcription factor 1 |
10.9 |
|
|
TEAD3 |
TEA domain family member 3 |
10.9 |
|
|
ETV6 |
ets variant 6 |
10.6 |
|
|
FOXA2 |
forkhead box A2 |
6.9 |
|
|
β-scaffold |
SOX2 |
SRY (sex determining region Y)-box 2 |
71.3 |
|
RUNX1 |
runt-related transcription factor 1 |
16.7 |
|
|
SOX4 |
SRY (sex determining region Y)-box 4 |
11.4 |
|
|
TFCP2 |
transcription factor CP2 |
10.7 |
|
|
SOX21 |
SRY (sex determining region Y)-box 21 |
9.0 |
|
|
NFATC1 |
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
7.8 |
|
|
SOX9 |
SRY (sex determining region Y)-box 9 |
7.7 |
|
|
|
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|
1 The top 30 DNA-binding transcription factors were identified in the highly expressed SAE-enriched list for n = 5 healthy nonsmokers. They were categorized by transcription factor family and sorted in descending order of expression within each category. |
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|
Hackett et al. BMC Genomics 2012 13:82 doi:10.1186/1471-2164-13-82 |
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