RNA-Seq quantification of examples of smoking-dependent changes in expression of ion channel-related genes expressed in the small airway epithelium. Smoking responsiveness of selected ion channels. A. CFTR - unchanged; B-D. Up-regulated. B. ABCC3; C. CACNG4; and D. CNGB1. E-F. Down-regulated. E. SLC13A2; and F. KCNC4. In all panels, each data point represents one individual.
Hackett et al. BMC Genomics 2012 13:82 doi:10.1186/1471-2164-13-82