Relative distribution of the expression of ubiquitous and SAE-enriched genes of healthy non-smokers in different functional categories. Gene ontology assignments were used to identify genes of 7 functional categories and the frequency distribution of expression level was determined in 1/2 log10 bins, starting with the threshold (RPKM 0.125 = -0.9 log10). The data is plotted separately for the ubiquitous genes (open symbols) and SAE-enriched genes (closed symbols) with the number and percentage of genes in each low, medium and high group. For each panel, for each group, listed is the number of genes, % of the total in that category, and median RPKM for n = 5 healthy nonsmokers (number with downward arrow). A. Transcription; B. Translation; C. Immunity; D. Signal transduction; E. Adhesion; F. Membrane receptors; and G. Ion transporters.
Hackett et al. BMC Genomics 2012 13:82 doi:10.1186/1471-2164-13-82