The 10 network clusters by the clusterMaker. (a) Expression of MCF7-T over MCF7 was color-coded in the clusters. (b) Expression of MCF7-F over MCF7 was color-coded. The circle-ended dashed edge in black represents a TF binding to the miRNA promoter, or denotes an upstream signaling protein regulating the miRNA. The grey solid edge indicates association between the cancer contexts and the protein coding genes (including miRNA target mRNAs). The blunt-ended solid edge in blue represents miRNA-mediated target mRNA inhibition. The color scale description is same with Figure 1.
Nam et al. BMC Genomics 2012 13:732 doi:10.1186/1471-2164-13-732