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Open Access Highly Accessed Research article

The arthritis severity locus Cia5a regulates the expression of inflammatory mediators including Syk pathway genes and proteases in pristane-induced arthritis

Max Brenner1 and Pércio S Gulko12*

Author Affiliations

1 Laboratory of Experimental Rheumatology, Center for Genomics and Human Genetics, The Feinstein Institute for Medical Research, 350 Community Drive Room 1240, Manhasset, 11030, NY, USA

2 The Elmezzi Graduate School for Molecular Medicine, Manhasset, USA

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BMC Genomics 2012, 13:710  doi:10.1186/1471-2164-13-710

Published: 19 December 2012

Additional files

Additional file 1:

Table S3. Functional categories related to angiogenesis and extra-cellular matrix turnover that were significantly down-regulated in DA.F344(Cia5a) synovium.

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Additional file 2:

Table S4. Functional categories related to pro-inflammatory signals, chemotaxis, and activation of myeloid cells that were significantly down-regulated in DA.F344(Cia5a) synovium*.

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Additional file 3:

Table S2. Detection frequency and expression values of cell subset specific genes in DA and DA.F344(Cia5a) synovial tissues.

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Open Data

Additional file 4:

Table S1. Primers and probes used for qPCR and the exons they targeted.

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Open Data